Lone Star College ShootingStudents wait outside an entrance to the Lone Star College North Harris campus after a shooting on campus on Tuesday, Jan. 22, 2013 in Houston. The shooting wounded three people and sent students fleeing for safety as officials placed the campus on lockdown, officials said.Akt is an intermediate in the antiapoptotic pathway activated by NICThe status of Akt activation in cells experiencing neglect in the presence or absence of Notch FL was determined. Phosphatidylinositol 3,4,5triphosphates generated through PI3K activity bind the PH domain of Akt enabling its translocation to the plasma membrane and subsequent phosphorylations on T308 and S473.11 These experiments were initiated because of the observation made in the HEK cell line that ectopically expressed NIC modulated the phosphorylation of Akt, specifically on S473 (Supplementary Figure 2A and B). Neglect triggered a loss of (endogenous) AktS473 phosphorylation, which was prevented in HeLa cells expre